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Phenylmethylsulfonyl-Fluoride(Pmsf)

Phenylmethylsulfonyl-Fluoride(Pmsf)

Synonyms α-Toluenesulfonyl fluoride; Benzylsulfonyl fluoride; PMSF; Phenylmethanesulfonyl fluoride

CAS Number: 329-98-6 Molecular Formula: C7H7FO2S Molecular Weight: 174.189 g/mol

Beilstein Registry Number: 2088311 EC Number: 206-350-2 MDL Number: MFCD00007424

Packaging size: 5 g

SKU 04800263
Price:
£74.90
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Description

Product Description

Phenylmethylsulfonyl-Fluoride(Pmsf)

Application Notes

Phenylmethylsulfonyl Fluoride inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase but not those from fish sources.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Inhibitor of trypsin; chymotrypsin and protease

Specifications
SKU 04800263
Application Notes Phenylmethylsulfonyl Fluoride inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase but not those from fish sources.
Beilstein Registry Number 2088311
Biochemical Physiological Actions Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.
EC Number 206-350-2
Format Needle-shaped Crystals
Half Life 1 hr. at pH 7.5(Lit.)
Hazard Statements H301-H314
Applications Inhibitor of trypsin; chymotrypsin and protease
Molecular Formula C7H7FO2S
Molecular Weight 174.189 g/mol
Pack Size 5 g
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
Physical Appearance White to Off-white Needle-shaped Crystals
Product Families Description Phenylmethylsulfonyl fluoride
Product Overview Phenylmethylsulfonyl-Fluoride(Pmsf)
Protein or Enzyme Type Activators, Inhibitors & Substrates
Purity ≥98%
RTECS Number XT8040000
Safety Symbol GHS05, GHS06
Storage and Handling Store at +4 °C.
Typical Working Concentration Effective concentration 15 to 175 ug/mL (Lit.)
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.